Sirona Biochem’s Chief Executive Officer, Neil Belenkie will be the company’s presenter. The presentation will be webcast live and a link to the webcast will be made available and announced at a later date.

Presentation details as follows:  

• Date and Time: 10:30am-11:00am EDT, May 30, 2013 
• Venue: Grand Hyatt, New York, NY, Estate 6 Room 
• Presenter: Neil Belenkie, Chief Executive Officer of Sirona Biochem

About Sirona Biochem Corp.
Sirona Biochem is a biotechnology company developing diabetes therapeutics, skin depigmenting and anti-aging agents for cosmetic use, biological ingredients and cancer vaccine antigens.  The company utilizes a proprietary chemistry technique to improve pharmaceutical properties of carbohydrate-based molecules. Sirona Biochem is the parent company of French-based biotechnology company, TFChem.  For more information visit www.sironabiochem.com.

About the Marcum MicroCap Conference
The Marcum MicroCap Conference is dedicated to introducing investors to the very best, undiscovered companies under $500 million in market capitalization. The Conference is expected to draw more than 1,000 attendees including senior personnel from almost 100 presenting public companies. This invitation-only event attracts institutional investors including top fund managers and qualified high net worth investors, who focus on small cap equities.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

For more information regarding this press release, contact:

Christopher Hopton
CFO
Sirona Biochem Corp.
Phone:  604.282.6064
Email: chopton@sironabiochem.com

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Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise.  Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem’s forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem’s business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.

I’d like to take this opportunity to summarize Sirona Biochem’s business and strategic growth over the past 7 months.

Financial:

In October 2012, Sirona’s share price hit a low of 4 cents and our market cap was $3 million CDN. We made the decision to raise money using a debt instrument to avoid a punitive equity financing. We raised $600,000 in debt which gave us the financial runway to grow the value of the company to a high of 14 cents per share and a market cap of more than $11 million on January 18^th 2013. February 22, 2013 we announced an equity financing target of $2.7 million and we closed the second tranche of this financing on April 30, 2013 having raised $2.4 million. Our monthly net burn rate is approximately $160,000.

Moving forward, in the public marketplace we intend to fully maximize the value of QX listing by engaging in a professionally designed and executed effort to present the Company to retail and institutional investors and capital raising sources in most major cities in the United States.

Strategy:

The decision was made in November that we would de-risk our business model and simplify our operations. Sirona Biochem committed to a business strategy of: science, patent, partner. The benefit of this model is the following:

• We focus on what we do best, and nothing else. 
• We don’t risk our treasury or future by trying to develop a compound beyond a new patent
  • Our expertise lies in the science and patenting process. We recognize that we do not have the finances, human resources or expertise to take a pharmaceutical compound through clinical studies and regulatory approval.
  • In the future, drug development will only be considered with pre-partnered technology where the major economic burden is assumed by the partnering entity.

With this level of strategic focus, we maximize our ability to create and patent innovative compounds which will be licensed and partnered. We also diversify our risk across multiple projects, increase our portfolio size more quickly and continue to build our credibility and reputation as experts in fluorination chemistry.

Operations:

In November we restructured the company and downsized our corporate head office by one position. In our laboratory in France we assessed every project in development and made the decision to focus our resources on two projects to ensure each would be completed and available for transaction within 6 months. All other projects were assigned a timeline for re-insertion into the development pipeline contingent on the successful completion of our two prioritized projects.

On November 5th we approached the French government to propose a second grant/partnership opportunity, building on the research and development grant we received for the skin lightening program.

On December 6^th we approached a second arm of the French government to propose an expansion of our laboratory facilities in the Cosmetic Valley of France. Our business growth relies on creating and patenting new innovative compounds. We will be expanding our scientific team in order to grow the number of projects under way and plan to do so by expanding our facility in the Cosmetic Valley in France.

We selected a new head office location in Vancouver. Our current lease is set to expire and an increase in rent was scheduled upon renewal. Our team worked hard to find another office where we will save money and support our goals for growth over the next 5 years.

We have created the growth plan for our laboratory in France. In the next 24 months we plan to add 19 new employees and almost triple the size of our facility. This growth plan is tied directly to our goal of significantly growing the number of projects we are able to undertake concurrently.

Business Development:

On March 20, 2013 we completed our skin lightening project and announced that both of our skin lightening compounds were successful in industry standard safety tests. This was an important milestone as we now have two compounds to license, doubling the potential value derived from this program.

We concluded development on our SGLT2 Inhibitor and completed the diligence package presenting the distinct advantages our compound has over its competition. The next phase of development for this compound will be led by a partner who has the experience and financial resources to shepherd a pharmaceutical compound through clinical testing, regulatory approval and launch to market.

In order to maximize our ability to connect with leaders in the pharmaceutical and cosmetic markets, we engaged 4 business development individuals on commission-only compensation agreements. These individuals have been introducing Sirona Biochem’s technology to targeted businesses around the world. We have received more than 20 qualified introductions for potential licensing, partnership and joint venture opportunities as a result of this business development initiative.

In the last 6 months we have attended and/or presented at the following meetings, conferences and events:

• In Cosmetics Asia (Bangkok)
• In Cosmetics Europe (France)
• Bio Partnering North America
• BIO International Convention (Chicago)
• BIOTECanada CEO Summit
• China (Beijing, Tianjin, Guangzhou)
• France (Rouen, Paris)
• New York

Our strategic process for optimizing the value of our technology is as follows: we connect with as many pharmaceutical, biotech, cosmetic and consumer health companies as possible that may have interest in our technology. Starting all of these discussions in parallel allows us to move the conversations forward within a predictable window of opportunity. These concurrent conversations create a competitive environment for our technology, maximizing its value within the marketplace.

Summary:

We are extremely proud of having raised $2.4 million in these challenging economic conditions; few other pre-revenue Canadian biotech companies have been able to generate the confidence and economic support that we have earned.

Our SGLT2 Inhibitor compound and our two skin lightening compounds each have multiple companies conducting diligence and our licensing plans are proceeding as per our expectations.

Multiple projects have been presented to us as opportunities for joint ventures and partnerships. Our reputation is growing as a leader in the science of fluorination and large multinational companies continue to communicate the value the benefits of our proprietary fluorination technology.

Moving forward we are strategically and operationally optimized to transition Sirona Biochem to its next phase of growth. Generating revenue and creating joint venture partnerships is our top priority and we are building the business to support these goals on an international scale.

Best Regards
Neil Belenkie
CEO, Sirona Biochem Corporation

About Sirona Biochem Corp.

Sirona Biochem is a biotechnology company developing diabetes therapeutics, skin depigmenting and anti-aging agents for cosmetic use, biological ingredients and cancer vaccine antigens.  The company utilizes a proprietary chemistry technique to improve pharmaceutical properties of carbohydrate-based molecules. Sirona Biochem is the parent company of French-based biotechnology company, TFChem.  For more information visit www.sironabiochem.com.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

For more information regarding this press release, contact:

Christopher Hopton, CFO
Sirona Biochem Corp.
Phone:  604.282.6064
Email: chopton@sironabiochem.com

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Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise.  Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem’s forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem’s business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.

Vancouver, British Columbia – May 3, 2013 – Sirona Biochem Corp. (“the Company”; TSX-V: SBM, OTCQX: SRBCF, Frankfurt: ZSB) is pleased to announce that it closed today equity and debt financings for gross proceeds of $975,000, bringing the total capital raise to $2.4 million to date in 2013. 

“We thank the investment community for their confidence in Sirona Biochem and our international team’” commented Neil Belenkie, Sirona Biochem’s Chief Executive Officer. “This capital infusion will support us to achieve our goal of licensing and partnering our innovative compounds. This is the most exciting time in our company’s history,” he added.

The total capital raise of $2.4 million consisted of the equity placement of $375,000 and the debt placement of $600,000, both of which closed today, and the equity raise of $1,424,500 that closed in March 2013.

Equity Financing

In the equity financing, a total of 3,750,000 units (each a “Unit”) were issued at a price of $0.10 per Unit.  Each Unit consisted of one common share of the Company and one transferable share purchase warrant (a “Warrant”). Each Warrant entitles the holder to purchase one additional common share of the Company at any time for two years at a price of $0.15 per share. Chris Verrico, a director of the Company, purchased 1,500,000 Units.

In connection with the equity placement, the Company will pay fees of $4,000 and issue 40,000 non-transferable finder warrants to Leede Financial Markets Inc., with each finder warrant exercisable into one common share for two years at an exercise price of $0.15 per share.

Debt Financing

In the debt financing, a total of $600,000 was raised by way loans to the Company. The loans are due 18 months from the date of advancement of the funds and accrue interest at a rate of 12% per annum. The Company also issued 4,374,815 transferable share purchase warrants (the “Bonus Warrants”) to the lenders. Each Bonus Warrant entitles the holder thereof to purchase one common share of the Company for a period of 30 months at exercise prices ranging from $0.10 to $0.12 per share.

Alex Marazzi, a director of the Company, participated in the debt financing in the amount of $30,000.

In connection with the debt placement, the Company will pay fees of $15,750 and issue 210,000 non-transferable finder warrants to various finders, with each finder warrant exercisable into one common share for 30 months at an exercise price of $0.10 per share.

Disclosure Related to Financings

The Company intends to use the proceeds from the equity and debt financings for research and development, operations, business development activities and general working capital.

The payment of all finders’ fees and the issuance of finder warrants in connection with the financings are subject to final approval by the TSX Venture Exchange (“TSX-V”).  All securities issued in connection with the financings are subject to a four-month hold period that expires on September 3, 2013.

This news release does not constitute an offer to sell or a solicitation of an offer to sell any of the securities in the United States.  The securities have not been and will not be registered under the United States Securities Act of 1933, as amended (the “U.S. Securities Act”) or any state securities laws and may not be offered or sold within the United States or to U.S. Persons unless registered under the U.S. Securities Act and applicable state securities laws or an exemption from such registration is available.

Warrant Extension

The Company reports that it will make an application to the TSX-V to extend the term of 10,215,000 warrants, which were originally issued on October 23, 2010 and are exercisable at $0.20 per share until October 23, 2013.  The Company is applying to extend the expiry date of these warrants to October 23, 2015. The exercise price for the warrants will remain the same.  The warrant amendments have been approved by the board of directors of the Company, subject to the receipt of TSX-V approval.

About Sirona Biochem Corp.
Sirona Biochem is a biotechnology company developing diabetes therapeutics, skin depigmenting and anti-aging agents for cosmetic use, biological ingredients and cancer vaccine antigens.  The company utilizes a proprietary chemistry technique to improve pharmaceutical properties of carbohydrate-based molecules. Sirona Biochem is the parent company of French-based biotechnology company, TFChem.  For more information visit www.sironabiochem.com.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

For more information regarding this press release, contact:

Julie Jang
Director, Communications
Sirona Biochem Corp.
Phone:  604.282.6065
Email: jjang@sironabiochem.com

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Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise.  Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem’s forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem’s business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations.  Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.

“We are pleased with the continued commitment from Ray Matthews in bringing awareness of Sirona Biochem to the investment community,” said Dr. Howard Verrico, Sirona Biochem Founder and Chairman of the Board. “Ray Matthews is well respected and will assist in the capital and institutional markets while we continue to focus on creating partnerships for our compounds and growing our organization,” said Neil Belenkie, Sirona Biochem Chief Executive Officer.

“Sirona Biochem has made significant scientific and organizational progress over the last few months, attracting the interest of international financial institutions and many of the world’s largest cosmetic and pharmaceutical companies.  I’m happy to be part of the company during this exciting stage of growth,” said Ray Matthews. 

About Sirona Biochem Corp.

Sirona Biochem is a biotechnology company developing diabetes therapeutics, skin depigmenting and anti-aging agents for cosmetic use, biological ingredients and cancer vaccine antigens.  The company utilizes a proprietary chemistry technique to improve pharmaceutical properties of carbohydrate-based molecules. Sirona Biochem is the parent company of French-based biotechnology company, TFChem.  For more information visit www.sironabiochem.com.

About Ray Matthews & Associates Inc.
Ray Matthews & Associates Inc (RM&A) is a strategic advisory firm focusing on corporate development, M&A, strategic planning and boutique IR services to Canadian and U.S.-based companies at all stages of development. For more information on RM&A Inc, please visit www.raymatthews.ca.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

For more information regarding this press release, contact:

Julie Jang
Director, Communications
Sirona Biochem Corp.
Phone:  604.282.6065
Email: jjang@sironabiochem.com

———————————————

Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise.  Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem’s forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem’s business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.

May 30, 2013, 10:30am EDT
Grand Hyatt, New York, NY
Room: Estate 6
CEO Neil Belenkie in attendance

The phototoxic potential of TFC-849 and TFC-723 was evaluated at a concentration range 0 to 1000 µg/ml for 1 hr on fibroblast cultures, exposed to the highest non-cytotoxic UVA irradiation dose (5 J/cm²).  Fibroblasts’ viability was assessed using the neutral red uptake method and compared in both irradiated and non-irradiated cultures. Neither compound (TFC-849 or TFC-723) showed phototoxicity in the concentration range tested.

The irritant potential of TFC-849 and TFC-723 was evaluated on reconstituted human epithelium (RHE) at concentrations 0.5%, 2.5% and 5% (w/v). The RHE viability was assessed using an MTT assay and both depigmenting agents, TFC-849 and TFC-723, showed no skin irritation in the concentration range studied.

“Having both TFC-849 and TFC-723 successfully complete all safety testing is a testament to our scientists and patented technology. Safe and effective skin lightening agents are at a premium in the lucrative cosmetic and dermatologic industries and we have two leading compounds. I’m extremely proud of our team,” said Neil Belenkie, Chief Executive Officer of Sirona Biochem.

It is estimated that more than $7.5 billion was spent on cosmetic skin lighteners in 2009 and that number is expected to exceed $10 billion by 2015.  Approximately 15% of the worldwide population invests in skin lightening products with Asia being the largest market. For dermatologists, medical conditions such as hyperpigmentation, melasma, vitiligo and rosacea are also contributing to the demand for safer and more effective skin lightening creams.

No animals were involved in the development and testing of Sirona’s skin lightening compounds.

About the Project

Sirona Biochem’s French subsidiary, TFChem received in November 2011 a $1.9-million grant. This project is co-financed by the European Union and Europe Witnesses in Haute-Normandie with the support of the European Regional Development Fund (E.R.D.F.). A consortium of partners – including the University of Rouen (LMSM EA4312), contract research organization Biogalenys, and TFChem – has been assembled to advance this project. The French government and European Union are looking to promote and initiate collaborative projects that are focused on the development of new products and services containing a high level of innovation.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

For more information regarding this press release, contact:

Julie Jang
Director, Communications
Sirona Biochem Corp.
Phone:  604.282.6065
Email: jjang@sironabiochem.com

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Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise.  Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem’s forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem’s business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.

“Going Global Innovation is an excellent initiative that promotes international R&D collaborations and we are very pleased to have been awarded this funding,” commented Sirona Biochem Chief Executive Officer, Neil Belenkie. “Sirona Biochem’s scientific programs have received worldwide interest and the contribution from Going Global helps to fund the related expenses for international meetings,” he added.

About Going Global Innovation
Going Global Innovation is the innovation, science and technology pillar of the Global Commerce Support Program (GCSP) at Foreign Affairs and International Trade Canada. The objectives of Going Global are to promote and enhance Canada’s international innovation efforts by supporting Canadian companies and/or researchers in pursuing collaborative international research and development opportunities through the development of partnerships with key players in other countries and economies.

About Sirona Biochem Corp.
Sirona Biochem is a biotechnology company developing diabetes therapeutics, skin depigmenting and anti-aging agents for cosmetic use, biological ingredients and cancer vaccine antigens.  The company utilizes a proprietary chemistry technique to improve pharmaceutical properties of carbohydrate-based molecules. Sirona Biochem is the parent company of French-based biotechnology company, TFChem.  For more information visit www.sironabiochem.com.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

For more information regarding this press release, contact:

Julie Jang
Director, Communications
Sirona Biochem Corp.
Phone:  604.282.6065
Email: jjang@sironabiochem.com

———————————————
Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise.  Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem’s forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem’s business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.