Vancouver, British Columbia – February 14, 2012 – Sirona Biochem Corp. (TSX-V: SBM, OTC: SRBCF, Frankfurt: ZSB) (the “Company”), a biotechnology company, announced today it has completed a pivotal proof of concept study of its biological inducer for recombinant protein manufacturing.
In the study, Sirona Biochem’s inducer produced more protein compared to a leading commercially available inducer at the same concentration. In addition, Sirona Biochem’s compound induced synthesis of a soluble recombinant protein in Escherichia coli for up to 24 hours.
“We believe we are on track to producing an inducer that is more stable, can be stored at room temperature and can improve protein yields for recombinant protein manufacturers, which could be particularly useful in producing insulin,” said Sean Cunliffe, Chief Business Officer of Sirona Biochem “The results of this study further validates our proprietary chemistry platform and its potential in improving upon existing carbohydrate molecules,” Mr. Cunliffe added.
Inducers are carbohydrates which trigger recombinant protein production. The quality of the inducer is key to the production process and can affect the quality and yield of the protein. Current inducers, because they are carbohydrates, are metabolically unstable, and require special handling conditions.
About Sirona Biochem Corp.
Sirona Biochem is a biotechnology company developing diabetes therapeutics, cancer vaccine antigens, skin depigmenting and anti-aging agents for cosmetic use, and biological ingredients. The company utilizes a proprietary chemistry technique to improve pharmaceutical properties of carbohydrate-based molecules. For more information visit www.sironabiochem.com.
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